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The simplest formulation contains semaglutide dissolved in a sterile solution, typically with a buffer to maintain optimal pH and bacteriostatic water as the solvent

Lefranois P, Xie P, Wang L , Tetzlaff MT, Moreau L, Watters AK, Netchiporouk E, Provost N, Gilbert M, Ni X, Sasseville D, Wheeler DA, Duvic M, Litvinov IV

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Increased Risk of Gallstones & Gallbladder Disease Rapid weight loss can trigger gallstone formation, leading to pain or the need for gallbladder removal