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The novel biguanide MC001 showed much stronger antitumor effect and relatively weaker proglycolytic activity compared with metformin as shown in vitro in colorectal cancer cells ( in vitro by modulating the AMPK-mTOR and androgen receptor signaling pathways ( In vivo , NT1014 reduced tumor weight by 61%, whereas metformin by only 32%

Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) and their influence on mucoadhesion

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The fractions of the drugs that were systemically absorbed or transported through trigeminal pathway did not contribute to the distribution of peptides to the brain