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Interestingly, the STEP-8 study 22 revealed a higher incidence of psychiatric events with liraglutide 3 mg (15.0%) compared to semaglutide 2.4 mg (5.6%) and placebo (10.6%)

En el ensayo cardiovascular SUSTAIN-6, semaglutida redujo MACE (muerte cardiovascular, infarto agudo de miocardio no fatal o ictus no fatal) vs placebo: HR 0,74 (IC 95% 0,580,95)

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valproic acid (a seizure control agent)