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GWAS have identified numerous genetic loci linked to UC, shedding light on the genetic factors that contribute to disease risk and progression

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Strikingly, in a large cross-sectional study ( n = 5725 females and n = 1061 males) menstruation was found as the main trigger factor for migraine episodes in female patients (78% of women) 69 , while postmenopausal women appear to have more similar migraine triggers to male migraine patients than fertile female patients concerning hormonal levels 69