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c , Top, volcano plot showing relative fold change (log 2 ) in ER-metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with antimycin compared to untreated

Research utilizing the Broad Institute's Connectivity Map indicates it influences the expression of over 4,000 genes (~31% of the human genome), shifting gene signatures from a pathological state back to a healthier, regenerative baseline

Eur J Gastroenterol Hepatol 24:179185

Furthermore, it has been found that more than 3.6 105 ha of carbonate rock area is contaminated with heavy metals associated with coal-fired zinc smelting activities under geochemical anomalies with high heavy metal backgrounds in northwest Guizhou Province [2]