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Generalized Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)

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The aggregation of microtubule-associated protein Tau is associated with a broad range of brain diseases generally termed tauopathies, which includes AD, progressive supranuclear palsy, argyrophilic grain disease, corticobasal degeneration and Picks disease (Lee et al., 2001

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