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While specific requirements can vary by provider, clients are commonly considered good candidates if they meet one of the following criteria: A BMI of 30 or higher (classified as obesity) A BMI of 27 or higher with at least one weight-related health condition, such as high blood pressure, high cholesterol, type 2 diabetes, prediabetes, or sleep apnea In addition, candidates should be in overall stable health, not pregnant or breastfeeding, and not have a personal or family history of certain medical conditions such as medullary thyroid carcinoma or MEN2 (Multiple Endocrine Neoplasia type 2)

These limitations do not invalidate the findings, but they do mean that the evidence is preliminary rather than definitive

Figure 2 3.1 Reactive oxygen species and oxidative stress Oxidative stress is widely recognized as a primary trigger of vitiligo

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