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There is also a physiological reason to expect the gastric arm to be self-limiting

L- amino acids are essential for protein synthesis and energy production, and mammals (including humans) synthesize amino acids almost exclusively in the L- configuration.75 In supplements, L- or D- may be more informed by bioavailability, as the body may better absorb the L form of one amino acid or the D form of another

Water Retention or Swelling: Mild edema may develop in some cases due to localized tissue repair activity

Read on for more on what that means, how clinical trials work, who may qualify, and what to do if a trial isnt an option for you (spoiler alert: you have options!)