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372 Ferroptosis also occurs in peripheral blood monocytes in SLE, with electron microscopy revealing characteristic ferroptosis features, such as decreased mitochondrial volume, increased mitochondrial membrane density and the disappearance of mitochondria

When this regulatory mechanism is impaired, SQOR accumulates abnormally, leading to a sharp decrease in testicular H 2 S and severe oxidative stress (elevated ROS levels and diminished antioxidants like glutathione and SOD)

Thus, we must discuss the potential regulation of epithelial integrity and barrier function under conditions of immune activation and inflammation

& Florian, T