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On day 9, probe trials were conducted by removing the hidden platform, allowing animals to search for 120 seconds

shows that 7nAChRs knockout mice that do not respond to cholinergic agonists, which in turn enhance the production of several cytokines and inflammatory markers, including tumor necrosis factor-alpha (TNF-) and interleukin-1 (IL-1) [65], this results from suppression of signal transduction cascade including PIK3/Akt and Nrf2 and upregulation of NF-B that represent a transcriptional factor capable of coordinating the inflammatory response, regulating the inflammatory gene expression [35, 66]

Magnesium is a vital mineral that supports several essential functions in the brain and body