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The specific adjustment should be individualized based on current glycemic control, hypoglycemia history, and treatment goals

In this study, the risk appeared to be independent of rapid HbA 1c reduction, a mechanism previously confirmed to increase PDR risk, suggesting that caution is required irrespective of HbA 1c when initiation is being considered

Dementia 23(3):493511 Thomson WM, Barak Y (2020) Tooth loss and dementia: a critical examination