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Both forms contain semaglutide, but they are different formulations with different dosing schedules and instructions for use

3.5.1 Background CFS, also known as Myalgic Encephalomyelitis (CFS/ME), is a complex disorder marked by persistent fatigue, cognitive impairment, and a range of physical symptoms that are not alleviated by rest (Knig et al., 2021

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A 2025 real-world analysis confirmed that extending the titration phase by 4-8 weeks (staying at each dose longer before escalating) significantly reduced GI side effects without meaningfully affecting 52-week weight loss outcomes