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Guo -X-X, Wang Y, Wang K, Ji B-P, Zhou F

In another THCA transcriptome data ( RRM2 gene in the whole biological behavior of tumors, we performed a pan-cancer analysis by the combination of TCGA and GTEx data, which showed that RRM2 was generally highly expressed in tumors of epithelial origin, such as THCA, esophageal carcinoma, and breast carcinoma, suggesting that its pro-carcinogenic mechanism is conserved by the cancer species

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It allows you to then set up your system, to assume that that's the case and to set up your environment rather than any single intervention