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In patients who already had substance use disorders, starting the GLP-1s was linked with a 31 per cent lower risk of emergency department visits, 26 per cent lower risk of hospitalizations, 25 per cent lower risk of suicidal thoughts or attempts, 39 per cent lower risk of overdose and 50 per cent lower risk of death

Patients who store reconstituted vials at room temperature for convenience are injecting degraded compounds that deliver minimal metabolic benefit, regardless of dosing frequency or injection technique

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IF combined with other eating interventions, such as liquid diet, protocol