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In a systematic review, researchers analyzed the gut microbiomes of patients with depression and found substantial differences in microbiome composition compared to healthy individuals, particularly in the abundance of certain bacterial genera, such as Prevotellaceae and Blautia [493, 494]

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These inconsistencies may be due to the small sample size of the included studies, differences in baseline characteristics of study participants, differences in study design such as follow-up duration or control group, and other factors