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Although it has recognized therapeutic value, the use of this injection of abobotulinumtoxinA 5 units for cosmetic purposes is generally not covered under Medicare or Medicaid, as coverage is usually limited to defined indications

[19] These licensed treatments offer a far safer, evidence-based alternative to unlicensed investigational compounds

doi: 10.3389/fonc.2021.648139

The limited number of treatments able to significantly reduce weight, as well as the risk of renewed weight gain from 6 months after the end of intervention, have been an obstacle for considering pharmacological treatment for obesity in patients with PsO or HS.15 Approved and marketed drugs in SpainOrlistat Orlistat is an inhibitor of the gastric and pancreatic lipases that block hydrolysis of triacyl glycerides and absorption of fatty acids through the intestinal endothelium