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Reduced inflammation was also demonstrated by Bolcas et al

Notably, AD and DM share numerous pathophysiological mechanisms, most notably the disruption of insulin signaling pathways in the brain

Diabetes Care 24 , 382391 (2001)

Lastly, nine F (420)-dependent reductases (FDR) from Mycobacterium smegmatis that utilize the deazaflavin cofactor F 420 H 2 were found to catalyze the transformation of AFG1, AFG2, AFB1, and AFB2, with AFG1 being the best substrate for all nine enzymes (Taylor et al., 2010)