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Inflammatory response in the CNS: Friend or foe

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After being cultured with various concentrations of ACE (0.01, 0.1, 1, 5, 10, 25, or 50 M) for six days, the size of the live cells, represented by green fluorescence, significantly decreased, and the number of dead cells, represented by red fluorescence, significantly increased, indicating that the growth of the organoids was significantly inhibited, as shown in Fig

This study also demonstrated a significant increase in mouse brain fluorescence intensity for DNZ-NLPs (60%) compared to free DNAzymes (6%), indicating that nanoliposomes effectively transported DNAzymes across the BBB