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Cryo-EM Structure of SCF FBXO22 bound to UNC10415667 C and NSD2 To determine if the phenyl group of UNC10415667 contributes to complex formation or promotes favorable contacts with FBXO22, we sought to determine the structure of the SCF FBXO22 complex bound to NSD2 through a conjugated form of UNC10415667 (UNC10415667 C )