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Semaglutide and other GLP-1 compounds work by mimicking glucagon-like peptide-1, a hormone that regulates appetite and glucose controlmaking them a science-backed option for managing the weight shift many women experience during menopause

doi: 10.1038/s41746-024-01043-6

Intravenous infusion of GLP-1 for 48 h in healthy human subjects increased muscle sympathetic nerve activity but had no effect on BP, norepinephrine plasma concentration, or the sympathetic/parasympathetic balance as estimated by the HR variability, suggesting that the increase in sympathetic drive is at least partially compensated by an increase in the parasympathetic activity [53]

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