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For more on the science behind these pathways, see our guide: How Does Retatrutide Work

Daily use supports a smooth, luminous finish

Official Injection Sites for GLP-1 Medications According to their FDA-approved prescribing information, GLP-1 medications semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) are administered as injections just under the skin (subcutaneous) in three areas: Abdomen avoid the 2 inches (5 cm) directly around the navel Thigh outer/front thigh Upper arm back of the upper arm All four FDA labels (Ozempic 1 , Zepbound 2 , Mounjaro 3 , Wegovy 4 ) explicitly state that patients should rotate injection sites with each dose

Retatrutide, a triple GIP/GLP-1/glucagon receptor agonist, normalized liver fat in 90 percent of patients after 48 weeks