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The age group of 4064 constituted the majority of incident patients over the entire period, and the least represented group overall was children and adolescents below the age of 18

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The Vascular Hypometabolism Hypothesis: Reframing Dementia as an Energy and Delivery Problem A growing body of evidence suggests that dementia and Alzheimers disease are driven less by isolated protein aggregates and more by a chronic failure of blood flow, nutrient delivery, and metabolic precision in the brain, a framework often described as the vascular hypometabolism hypothesis [4, 5]

12 , eaay1359 (2020)