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JAMA Ophthalmol 134(12):13651372 Sharma N et al (2017) Comparison of oral Voriconazole versus oral Ketoconazole as an adjunct to topical Natamycin in severe fungal keratitis: a randomized controlled trial

15 - 17 Study 1419 was a phase III open-label, multi-centre, single-arm, investigator-sponsored trial with linked data from 4 predecessor studies (F0206S, F0375G, F0632G, and F0671G)

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Summary-level data for 4 enzymes including alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma glutamyltransferase (GGT), was available from the UK Biobank