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Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

While these are typically only relevant in diagnostic settings, any drug affecting pituitary function or hormone levels could theoretically impact sermorelin therapy

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Novo is trading around 20% lower before the opening bell on Friday, while competitor Eli Lilly as well as other companies in the weight loss space, including Viking Therapeutics, Amgen, Biohaven and Structure Therapeutics traded higher in the premarket, Seeking Alpha reported