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Transpersulfidation processes also participate in the detoxification of H 2 S/HS , and several enzymes in the mitochondrial pathway for H 2 S/HS consumption catalyze transpersulfidation steps, such as SQOR and rhodanese

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Symptoms of glutathione synthetase deficiency may include: Seizures Hampered reaction to speech and physical stimuli Poor coordination Intellectual disability Vulnerability to bacterial infections Low glutathione levels are also associated with a large number of disorders, including some types of cancer and AIDS