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This effect is in contrast to PKC activators, which have been used in neurodegenerative disorders such as Alzheimers disease

In post-marketing reports, sitagliptin, saxagliptin, linagliptin, and alogliptin have been associated with hypersensitivity reactions, including anaphylaxis, angioedema, and more severe blistering skin conditions, including Stevens-Johnson syndrome (85)

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Studies examining crushed or severed peripheral nerves in rats found that BPC-157-treated animals recovered motor and sensory function significantly faster than controls, with histological evidence of improved axonal regeneration and reduced scar tissue formation at injury sites