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At the end of treatment, mice were euthanized by asphyxiation with CO 2 and peripheral blood, spleen single cell population were analyzed for the ROS, ferroptosis levels by DCF and Bodipy-C11 staining followed by flow cytometry analysis

This association was further validated using teduglutide, which upon administration showed a beneficial outcome by reducing de novo acute GVHD and steroid refractory GVHD in multiple mouse models

CCK-A receptor antagonists increase calorie intake and reduce satiety, suggesting a possible role of endogenous CCK in appetite regulation.21 CCK may be a very short-term modulator of appetite