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Methods: A total of 855 patients who attended the First Affiliated Hospital of Shandong First Medical University from January 2020 to May 2023 were selected as the study participants, who were divided into the training set (598 cases) and the validation set (297 cases) using a simple random sampling method at a ratio of 7:3

Results DHT treatment significantly decreased KGN cell viability, MMP and ATP levels, increased LDH release, ROS, MDA, iron ions and LPO content, up-regulated Cytochrome C expression, and down-regulated Ferritin, TFAM, and GPX4 expression