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In addition, berberine can properly restore the levels of 3-nitrotyrosine (3-NT), COX 2, glial fibrillary acidic protein (GFAP), and sirtuin 1 in the hippocampus (Sadraie et al., 2019)

A 2012 prospective study of 278 postmenopausal women found that intentional weight loss of roughly 7.7 kg produced a 13.4% reduction in free estradiol and a 9.9% reduction in total estradiol, along with a 16.2% increase in SHBG

Our findings are consistent with the oxidative stress suppressive effect of NTZ that underpins its antiviral effect against the influenza-A virus (Huang et al., 2023) and the chemoprophylactic action in breast cancer (Pal et al., 2020)

Lianli L, Mao J, Wang X et al