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The six strains below have the strongest evidence base for supporting gut health during GLP-1 therapy

Caco-2 cells were grown in Minimal Essential Medium with Earles Balanced Salts (MEM/EBSS, Cytiva) medium supplemented with 10% fetal bovine serum and 1% penicillinstreptomycin and 25 mM HEPES

We calculated the median Jaccard index within each cluster

For a deep dive into the different formulation options available across providers, our guides on tirzepatide with methylcobalamin and tirzepatide with niacinamide explain the science behind each variation