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Controlled feeding trials showed that sulfur amino acid (SAA) restricted diets can lead to significant reductions in body weight (BW) and waist circumference (WC) after only 4 weeks of intervention (116), as well as improvements in cardiometabolic disease risk biomarkers
[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)
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