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In addition, other studies indicated that Zn supplementation prevented T2DM-induced liver injury through the activation of the Nrf2-MT-mediated antioxidative pathway [154]

These protective effects involve activation of cell survival pathways and may include antioxidant mechanisms, though the precise molecular pathways mediating cytoprotection require further elucidation

Glutathione serves as a coenzyme contributing a thiolate as a base in the isomerase mechanism, which also involves the active-site Tyr9 and Arg15

In the context of SIBO, a holistic approach involves integrating liver support, herbs, and bile flow promotion into a comprehensive treatment plan