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Retatrutide is not yet available The earliest timeframe for approval is 20262027, after the final Phase 3 trials conclude

The risk of bias was graded as low, unclear or high via a systematic assessment on five domains: randomization process, deviations from intended interventions, missing outcome data, measurement of the outcome and selection of the reported result

People who took semaglutide in a regular clinical setting lost weight in a way that was similar to what was seen in controlled clinical studies

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