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Research Applications This selective activity makes AOD9604 an attractive candidate for obesity treatment and body composition optimization research, as it theoretically provides the metabolic benefits of growth hormone for fat reduction without the growth-promoting effects that could stimulate cancer cell proliferation, cause acromegaly-like symptoms, or induce insulin resistance

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Epigenetic and Cellular Reprogramming: By blocking NNMT-mediated methylation of nicotinamide, preserves NAD salvage pathway activity, increases SIRT-1 signaling, reduces histone deacetylation, and promotes metabolic reprogramming toward oxidative phosphorylation and glycolysis balance, supporting tissue repair and energy homeostasis 1-4