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Description

In contrast, strategies using growth hormone-releasing factor (GRF)/growth hormone-releasing hormone (GHRH) analogues to induce physiological increases of GH and preserve the insulin-like growth factor-1 (IGF-1) negative feedback have been shown to correct metabolic abnormalities and body composition changes associated with low GH levels with fewer side effects, particularly with regard to hyperglycemia [58]

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10.1097/00004691-199201000-00016 J

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SURMOUNT-1 Trial (Jastreboff et al., 2022): Even at the 2.5 mg starting dose, participants achieved 16% weight loss

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Epilepsia 2005;46:16251632

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