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However, these findings are mostly limited to single models, lacking data on distinct DR stages, ocular targeted delivery, long-term safety and efficacy, and comparisons with first-line clinical therapies

Patients with anemia (e.g., sideroblastic anemia, thalassemia) may experience decreased iron absorption during high dose ascorbic acid therapy

Although rare, serious side effects may occur including metabolic acidosis, kidney stones, decreased sweating leading to hyperthermia, and acute angle-closure glaucoma

A group of 58 people with psychotic disorders taking neuroleptics for 12 months was subjected to assessments of MetS, insulin resistance, and MTHFR C677T and A1298C polymorphisms