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Additionally, the BBB regulates substance transport into and out of the CNS, ensuring the chemical stability of the neuronal milieu and supporting normal neuronal metabolism, which is vital for the optimal functioning of the brain's 86 billion neurons

Inhibitory peptides from tuna protein simulations indicate that traditional hydrogen bond interactions, attractive charge interactions, and salt bridges play an important role in the interaction of EEAK with key residues of xanthine oxidase (eg, Glu802, Arg880, and Glu1261) (Yu et al., 2021)

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Ankle replacement has also become a viable option