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Ritlecitinib (Litfulo) is a kind of effective oral, selective JAK3 / TEC covalent kinase inhibitor

The high levels of circulating FFAs cause worsening of the insulin resistance which perpetuates a vicious cycle [6] and further liver dysfunction, inherently part of non alcoholic fatty liver disease

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[11] [12] Dietary recommendations: Focus on nutrient-dense foods lean proteins, vegetables, wholegrains, legumes, and healthy fats to maximise nutritional intake despite reduced appetite