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Second, although our data indicate that Vutiglabridin and GLP-1 RAs act through complementary mechanisms, the detailed molecular crosstalk between these pathways has not yet been fully elucidated

Cazzola M, Bettoncelli G, Sessa E, Cricelli C, Biscione G

The GHK sequence itself is naturally present in collagen and SPARC (Secreted Protein Acidic and Rich in Cysteine) protein, suggesting it functions as an emergency response molecule released during tissue injury through protein breakdown