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You may suffer from tingling and numbness due to nerve damage, as well as anemia that can manifest as weakness and pallor

As one of the two active forms of B12, methylcobalamin is required for several essential processes including: Conversion of homocysteine to methionine (thus lowering homocysteine concentrations) as part of the methylation cycle Generation of S-adenosyl methionine (SAMe) an important methyl donor involved with over 200 enzymes required for cell growth, maturation and specialisation Supplying methyl groups required for various reactions, including generation of acetyl-CoA The only cobalamin which can regulate sleep and wake cycles 12 13 possibly due to the fact that it does not require conversion as it is already in its active form

A deficiency in this essential vitamin is often easily noticeable

(November 2013)