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Side effects are rare but may include nausea, mild headaches, or allergic reactions in some individuals
This cascade can lead to: vascular injury kidney inflammation oxidative stress blood clot formation neurological damage In other words, homocysteine may act like the smoke alarm, while cytokines are the fire
S1E and Supplementary uncropped Western blots Fig
Mechanistically, this synergy involves concurrent suppression of survival pathways (AKT/mTOR) and amplification of pro-death signals (JNK/caspase-3) [16]
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