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Briefly, thiols were derivatized with 7-fluorobenzo-2-oxa-1,3-diazole-4-sulphonate, and chromatography was carried out on a C18 reversed-phase column with a mobile phase of 0.1 M potassium phosphate buffer (pH 2.1) with 5 % (vol/vol) acetonitrile

(2023, June 15)

doi:10.1016/S0140-6736(23)01302-8 99

( Bacillus subtilis and rheinan anthraquinone from rhubarb with anti-inflammatory activity (2025) designed an 18-glycyrrhetinic acid prodrug nanomicelle that, when combined with Lactobacillus rhamnosus GG, repaired the intestinal barrier and inhibited microglia-mediated neuroinflammation, thereby alleviating UC and concomitant depressive-like behaviors