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This educational page outlines a once-daily subcutaneous approach dosed in milligrams, with a dilution chosen so doses land on easy-to-read insulin-syringe marks

Endocrinology 161 (2), bqaa001

Perhaps the most important corrective for anyone imagining a performance benefit comes from a study that expressed the E-peptides alone, using an inactivating mutation to strip out mature IGF-I so that only the E-domains contribution remained