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The trial used unmodified GLP-1 without absorption enhancers, without nanocarrier formulations, without any of the technologies that modern intranasal peptide research employs to improve bioavailability

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Tesamorelin was developed under the brand name Egrifta and received FDA approval for reducing excess visceral fat in HIV-associated lipodystrophy, making it one of the few GHRH analogs with both clinical trial data and regulatory approval behind it

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