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Aditi Kantipuly and (the other) Peter Singer made the case in STAT in March 2026: BMI thresholds derived from American populations miss obesity in Asian patients, who face greater cardio-metabolic risk at lower BMI

What the Research Shows About Missed Doses and Weight Loss Outcomes Clinical trials of semaglutide have not specifically isolated the effect of single missed doses, but observational data from real-world weight loss programs shows that patients with high medication adherence (95% of scheduled doses) achieve 1522% body weight reduction after one year, while those with lower adherence (7080%) typically achieve 812%

Consistency matters more than perfect timing

They can weigh the potential risks and benefits of doing so, and together, you can come up with the best treatment plan to help you reach your weight loss goals