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Individuals with significant body weight to lose, typically those with a BMI that qualifies for GLP-1 therapy and who have 30% or more body weight to lose, may benefit from the more aggressive metabolic intervention this combination provides

Such strategic protection of potential new pipelines could see market leaders like Novo Nordisk and Eli Lilly continue to dominate this space for years to come

Microbiota variables included an abundance of 699 bacterial species present in at least 20% of MetaCardis patients corrected for microbial load and the first 10 principal components from a PCA of relative microbial gene abundances 31,41

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