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As a result, this leads to the accumulation of PLOOHs, which in turn cause rapid and irreparable cytoplasmic membrane damage and ultimately cell death (Shintoku et al., 2017)

doi: 10.1016/j.fct.2017.06.044 185 HanZCenCOuQPanYZhangJHuoDet al

These peptides are part of ongoing research into their therapeutic benefits, especially in the context of injury recovery and inflammation reduction

Analysis of cell death (necrosis versus apoptosis): SH-SY5Y cells were cultured in 6-well plates, preincubated for 2 hours in FBS-free culture medium, and then treated with guarana, caffeine, taurine, and their combinations for 4 hours in DMEM: F12 medium (without FBS)