About the Reviewer This article was written and medically reviewed by Dr
Similarly, lactotransferrin (LTF) on cancer cell membranes promotes ferroptosis by increasing intracellular iron levels [53]
A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient
Further according to Professor Khavinson, epithalamin augments the in vitro outgrowth of explants from the pineal gland but not from other tissues and has been found to offer the following anti-aging and longevity benefits [6, 7]: Increases melatonin production in rat pineal glands Improves immunological parameters in animals (rats and mice) Exhibits anticarcinogenic effects in various experimental models Stimulates antioxidant defenses Restores reproductive function in old rats There is clear evidence from clinical trials that the peptide increases the lifespan of animals (namely rats, mice, and fruit flies), and exhibits geroprotective activity in humans