what to expect starting semaglutide How Do You Know When GLP-1 Is Working? Starting semaglutide felt like a

Hinojosa explains

Tizepatide (aka Mounjaro and Zepbound) is often referred to as a GLP-1, but uniquely activates both GIP and GLP-1 hormone receptors

SURPASS-5 (NCT04039503) was a 40-week double-blind trial that randomized 475 adult patients with type 2 diabetes mellitus with inadequate glycemic control on insulin glargine 100 units/mL, with or without metformin, to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or placebo

The primary interaction concern with tirzepatide involves its effect on gastric emptying, which can influence the absorption kinetics of concomitantly administered oral medications