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Straight answer to this is NO

That said, weight gain may occur in people with hypothyroidism due to the accumulation of excess salt and waterbut only a small amount of weight gain (5-10 pounds) can be attributed to the thyroid

Side Effects Profile Side effects are predominantly gastrointestinal, with both medications sharing nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite, as outlined in Understanding the Side Effects of Semaglutide and Tirzepatide: A Comprehensive Guide for Patients

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